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Red Light Therapy for Dry AMD: The Science, the Evidence, and My Clinical Approach
Two devices, Valeda and Eyelight, now have clinical trial data supporting the use of photobiomodulation in intermediate dry AMD. Dr Leo Sheck reviews the science behind red light therapy, the Lightsite I–III and Eyelight trial results, and presents his clinical approach to selecting and monitoring patients for PBM treatment.

Red Light Therapy for Dry AMD: The Science, the Evidence, and My Clinical Approach
Two devices, Valeda and Eyelight, now have clinical trial data supporting the use of photobiomodulation in intermediate dry AMD. Dr Leo Sheck reviews the science behind red light therapy, the Lightsite I–III and Eyelight trial results, and presents his clinical approach to selecting and monitoring patients for PBM treatment.

Why some New Zealanders are stuck on monthly eye injections, and the case for funding Eylea HD?
The current Pharmac Special Authority criteria leave two groups of patients with neovascular AMD and diabetic macular oedema stranded on monthly eye injections: those established on Eylea before Vabysmo was funded, and those who respond poorly to Vabysmo. On 28 April 2026, Dr Leo Sheck submitted a formal Pharmac funding application for Eylea HD (aflibercept 8 mg) with revised Special Authority criteria designed to close this gap. Endorsed by Macular Degeneration New Zealand, Ophthalmology New Zealand, Eye Health Aotearoa, and the New Zealand Save Sight Society. Read the full submission and proposed criteria.

Why some New Zealanders are stuck on monthly eye injections, and the case for funding Eylea HD?
The current Pharmac Special Authority criteria leave two groups of patients with neovascular AMD and diabetic macular oedema stranded on monthly eye injections: those established on Eylea before Vabysmo was funded, and those who respond poorly to Vabysmo. On 28 April 2026, Dr Leo Sheck submitted a formal Pharmac funding application for Eylea HD (aflibercept 8 mg) with revised Special Authority criteria designed to close this gap. Endorsed by Macular Degeneration New Zealand, Ophthalmology New Zealand, Eye Health Aotearoa, and the New Zealand Save Sight Society. Read the full submission and proposed criteria.
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Fewer Injections, Better Outcomes? The Shift Toward Longer-Lasting Anti-VEGF Treatments
Newer anti-VEGF agents are extending dosing intervals for patients with retinal disease. In this NZ Optics article, Dr Francesc March de Ribot and I review the evidence, discuss non-responders, and examine what's next, including the current Pharmac funding gaps for New Zealand patients.
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Fewer Injections, Better Outcomes? The Shift Toward Longer-Lasting Anti-VEGF Treatments
Newer anti-VEGF agents are extending dosing intervals for patients with retinal disease. In this NZ Optics article, Dr Francesc March de Ribot and I review the evidence, discuss non-responders, and examine what's next, including the current Pharmac funding gaps for New Zealand patients.

Lowering Intraocular Pressure in Myopic Maculopathy? The Evidence for IOP as a Modifiable Risk Factor
Emerging evidence links higher intraocular pressure to atrophy progression in myopic maculopathy. Dr Leo Sheck reviews the mechanistic rationale, the clinical data, and proposes a practical treatment framework for clinicians managing high myopia.

Lowering Intraocular Pressure in Myopic Maculopathy? The Evidence for IOP as a Modifiable Risk Factor
Emerging evidence links higher intraocular pressure to atrophy progression in myopic maculopathy. Dr Leo Sheck reviews the mechanistic rationale, the clinical data, and proposes a practical treatment framework for clinicians managing high myopia.

Eye Health Research Review - February 2026
The latest issue of Eye Health Research Review was published in February 2026. You can find my discussion on the latest ophthalmic research to update your clinical knowledge here.

Eye Health Research Review - February 2026
The latest issue of Eye Health Research Review was published in February 2026. You can find my discussion on the latest ophthalmic research to update your clinical knowledge here.
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Transforming dry AMD treatment with AI
Dry AMD is no longer an untreatable disease. Find out with Dr Leo Sheck on how to accurately assess dry AMD and his approach in traversing this rapidly evolving field.
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Transforming dry AMD treatment with AI
Dry AMD is no longer an untreatable disease. Find out with Dr Leo Sheck on how to accurately assess dry AMD and his approach in traversing this rapidly evolving field.

A guide on how to manage pathological myopia poorly
Like you, I find management of pathological myopia challenging. As a result, I compiled a set of principles to avoid in the management of pathological myopia. This set of principles have been popular and useful for my registrars and ophthalmic nurses, and I hope you find them useful too.

A guide on how to manage pathological myopia poorly
Like you, I find management of pathological myopia challenging. As a result, I compiled a set of principles to avoid in the management of pathological myopia. This set of principles have been popular and useful for my registrars and ophthalmic nurses, and I hope you find them useful too.

Using AI for hydroxychloroquine retinal toxicity screening
A short report and Google Colab implementation of HCQuery, a novel algorithm for detection of hydroxychloroquine retinal toxicity

Using AI for hydroxychloroquine retinal toxicity screening
A short report and Google Colab implementation of HCQuery, a novel algorithm for detection of hydroxychloroquine retinal toxicity
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Beyond Spontaneous Resolution: Understanding When and Why to Treat Central Serous Chorioretinopathy
Unravel the complexities of Central Serous Chorioretinopathy (CSC). While many acute cases resolve spontaneously, learn when occupational needs or chronic presentations necessitate intervention. Discover why photodynamic therapy often stands out as the preferred treatment for its ability to address diffuse leakage and potentially lower recurrence risks.
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Beyond Spontaneous Resolution: Understanding When and Why to Treat Central Serous Chorioretinopathy
Unravel the complexities of Central Serous Chorioretinopathy (CSC). While many acute cases resolve spontaneously, learn when occupational needs or chronic presentations necessitate intervention. Discover why photodynamic therapy often stands out as the preferred treatment for its ability to address diffuse leakage and potentially lower recurrence risks.
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Why do you want your next patient's cataract surgery to be under topical anaesthesia?
It is safer, with possibly lower risk of day-one 'patch-off' vision loss, and has faster recovery time.
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Why do you want your next patient's cataract surgery to be under topical anaesthesia?
It is safer, with possibly lower risk of day-one 'patch-off' vision loss, and has faster recovery time.
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How many injections, on average, does a patient need for wet AMD?
This is a common question from my patients with wet AMD (neovascular AMD). Here I present two studies discussing the injection burden over time.
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How many injections, on average, does a patient need for wet AMD?
This is a common question from my patients with wet AMD (neovascular AMD). Here I present two studies discussing the injection burden over time.
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How to convey complex medical information to my retinal patients?
You will need to do this well to improve clinic attendance, adherence to treatment, and have happy patients!
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How to convey complex medical information to my retinal patients?
You will need to do this well to improve clinic attendance, adherence to treatment, and have happy patients!
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In wet AMD, what are the benefits of the newer generation (Vabysmo and Eylea HD) anti-VEGFs over the older generation (Eylea, Avastin)?
How do the first, second and third generation anti-VEGF differ?
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In wet AMD, what are the benefits of the newer generation (Vabysmo and Eylea HD) anti-VEGFs over the older generation (Eylea, Avastin)?
How do the first, second and third generation anti-VEGF differ?

How does the FDA approval of Pegcetacoplan (Syfovre) and Avacincaptad pegol (Izervay) help NZ AMD patients with geographic atrophy?
The US FDA approved the use of pegcetacoplan (Syfovre) and avacincaptad pego (Izervay) for the treatment of geographic atrophy (GA) in 2023. How can this help GA patients in New Zealand?

How does the FDA approval of Pegcetacoplan (Syfovre) and Avacincaptad pegol (Izervay) help NZ AMD patients with geographic atrophy?
The US FDA approved the use of pegcetacoplan (Syfovre) and avacincaptad pego (Izervay) for the treatment of geographic atrophy (GA) in 2023. How can this help GA patients in New Zealand?

Will switching to Vabysmo from Eylea lead to less frequent injections in neovascular AMD?
A patient came to see me wanting Vabysmo for his neovascular AMD. He is looking at delaying retirement and even selling down asset to fund for this treatment. How would I advise him?

Will switching to Vabysmo from Eylea lead to less frequent injections in neovascular AMD?
A patient came to see me wanting Vabysmo for his neovascular AMD. He is looking at delaying retirement and even selling down asset to fund for this treatment. How would I advise him?
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Falls and dementia in the elderly – is cataract surgery part of the solution?
Cataracts, dementia and falls are all common, yet debilitating, health conditions of the elderly. Here I examine the evidence for cataract surgery and its link to reducing the risk of dementia and falls, and how improving access to this surgery is likely to benefit our New Zealand cataract patients.
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Falls and dementia in the elderly – is cataract surgery part of the solution?
Cataracts, dementia and falls are all common, yet debilitating, health conditions of the elderly. Here I examine the evidence for cataract surgery and its link to reducing the risk of dementia and falls, and how improving access to this surgery is likely to benefit our New Zealand cataract patients.
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Improving outcome in central retinal artery occlusion (CRAO) - is thrombolysis the answer?
The use of intravenous (IV) thrombolytic therapy, namely tissue plasminogen activator (tPA), is the current mainstay treatment for cerebral ischemic stroke. But what role could it play in CRAO? I review the evidence and provide some insights on how we can approach the treatment of CRAO in clinical practice.
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Improving outcome in central retinal artery occlusion (CRAO) - is thrombolysis the answer?
The use of intravenous (IV) thrombolytic therapy, namely tissue plasminogen activator (tPA), is the current mainstay treatment for cerebral ischemic stroke. But what role could it play in CRAO? I review the evidence and provide some insights on how we can approach the treatment of CRAO in clinical practice.
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Insights from recent ophthalmic publications August 2023
My August 2023 Research Review article summarising the latest ophthalmic publications - approved for CME points by RANZCO, RNZCGP and The College of Nurses Aoteroa.
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Insights from recent ophthalmic publications August 2023
My August 2023 Research Review article summarising the latest ophthalmic publications - approved for CME points by RANZCO, RNZCGP and The College of Nurses Aoteroa.
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Complement inhibition for the treatment of non-neovascular (dry) AMD
Are the newly FDA-approved Pegcetacoplan and Avacincaptad Pegol a game-changer for treating non-neovascular (dry) AMD? Here are my thoughts.
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Complement inhibition for the treatment of non-neovascular (dry) AMD
Are the newly FDA-approved Pegcetacoplan and Avacincaptad Pegol a game-changer for treating non-neovascular (dry) AMD? Here are my thoughts.

An unusual cause of "floaters"
A patient with a blurred spot in his vision in the right eye. Examination shows a Weiss ring. Is the posterior vitreous detachment the cause of his symptoms?

An unusual cause of "floaters"
A patient with a blurred spot in his vision in the right eye. Examination shows a Weiss ring. Is the posterior vitreous detachment the cause of his symptoms?

Assessment of Vision Loss without Electrophysiology
Sometimes patients can present with vision loss, but despite a detailed assessment, no obvious cause is found. Here I demonstrated three useful techniques on the Spectralis viewing platform to help assess patients with vision loss of unclear cause.

Assessment of Vision Loss without Electrophysiology
Sometimes patients can present with vision loss, but despite a detailed assessment, no obvious cause is found. Here I demonstrated three useful techniques on the Spectralis viewing platform to help assess patients with vision loss of unclear cause.

What is Zaltrap, and how is it used in retinal diseases?
You may come across Zaltrap, or ziv-aflibercept, in treating retinal disease. Exactly what is this, and when is it used in intravitreal injections? This post will answer your questions.

What is Zaltrap, and how is it used in retinal diseases?
You may come across Zaltrap, or ziv-aflibercept, in treating retinal disease. Exactly what is this, and when is it used in intravitreal injections? This post will answer your questions.

Six steps to more comfortable intravitreal injections
Most patients do not look forward to their intravitreal injections. Here I outline six techniques to ensure my intravitreal injections are as pain-free as possible.

Six steps to more comfortable intravitreal injections
Most patients do not look forward to their intravitreal injections. Here I outline six techniques to ensure my intravitreal injections are as pain-free as possible.

Comprehensive Assessment of Geographic Atrophy - Optical Coherence Tomography Classification
This post will discuss the most recent literature surrounding OCT characterisation of geographic atrophy.

Comprehensive Assessment of Geographic Atrophy - Optical Coherence Tomography Classification
This post will discuss the most recent literature surrounding OCT characterisation of geographic atrophy.

Comprehensive assessment of geographic atrophy - general concepts and autofluorescence imaging findings
This post will summarise the recent trial of using Pegcetacoplan for the treatment of GA. Furthermore, we will look at the assessment of GA using different imaging modalities to help inform the risk of vision loss and to identify patients who maybe suitable for treatment when it becomes available.

Comprehensive assessment of geographic atrophy - general concepts and autofluorescence imaging findings
This post will summarise the recent trial of using Pegcetacoplan for the treatment of GA. Furthermore, we will look at the assessment of GA using different imaging modalities to help inform the risk of vision loss and to identify patients who maybe suitable for treatment when it becomes available.

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